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FAMILIAL HYPERCHOLESTEROLEMIA

A DIAGNOSIS AND

TREATMENT CHALLENGE

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high levels of “bad cholesterol” in the blood (low density lipoprotein or LDL). Individuals with this disorder have a higher risk of heart disease and stroke—the leading causes of death worldwide(1).

(1) Source: World Health Organization.
Although FH is a common genetic disorder, diagnosis rates are particularly low. In 2009, Sanofi and the biotechnology company Regeneron joined forces to develop Praluent®, a human monoclonal antibody that reduces LDL cholesterol levels for patients with familial or non-familial hypercholesterolemia not controlled by statins. Praluent® was approved in 2015 by the United States health authority, the Food and Drug Administration (FDA), as well as the European Commission and is now available in the United States, Germany, Austria, and Scandinavian countries.

Familial hypercholesterolemia, a genetic disorder.

BACK PAIN

AN OVER-THE-COUNTER TREATMENT FOR CHRONIC PAIN

One in eight people in the United States suffers from back pain.

More than 42 million people in the United States suffer from chronic back pain(1).

(1) Source: 2011 Gallop Study.
In 2014, true to its commitment to patient-driven innovation, Sanofi’s Consumer Healthcare entity introduced Icy Hot® SmartRelief™ Back Pain Therapy, an advanced, affordable, noninvasive solution to quickly relieve pain. This medical device available without prescription uses TENS (Transcutaneous Electrical Nerve Stimulation) technology to send electrical impulses (of patient-adjusted intensity) to the painful areas. It blocks pain and stimulates endorphin release. This treatment option, recommended by healthcare professionals across the United States, is both reusable and rechargeable. Following the success of the original product in the United States, Icy Hot® Smart Relief™ Knee & Shoulder Pain Therapy was introduced in 2015 to help those suffering from shoulder and knee pain.